Strange case of unexplained vision loss

We recently published a case study of a person who has suffered unexplained vision loss. Despite showing no evidence of any problems or dysfunction in her early visual pathway and pretty much normal retinotopic maps in the visual cortex, she has progressively lost her vision. The scotoma grew mostly in a clockwise fashion across her visual field without respecting the meridians, which would typically be a sign of a cortical source of the vision loss. In addition, she has severe deficits with visual processing, especially any visual functions that involve spatial integration, such as contour integration, illusory shapes, or detecting global motion. We cannot explain this pattern of results but it is a very interesting case that should be part of the scientific literature.

CW-Visual-Fields

Moutsiana, C, Soliman, R, de-Wit, L, James-Galton, M, Sereno, MI, Plant, GT, & Schwarzkopf, DS (2018). Unexplained progressive visual field loss in the presence of normal retinotopic maps. Frontiers in Psychology 9: 1722.

Optimal design for MAPS experiments

Nonie Finlayson published a series of experiments in which we explore the optimal design for experiments using our Multiple Alternatives Perceptual Search (MAPS) task for estimating perceptual biases at several visual field locations. We show that the MAPS task does not tend to result in a decision bias to select the middle of the candidate range but that feedback after every trial modulates estimates of perceptual biases.

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Finlayson, NJ, Manser-Smith, K, Balraj, A, de Haas, B, & Schwarzkopf, DS (2018). The optimal experimental design for Multiple Alternatives Perceptual Search. Attention, Perception & Psychophysics

Thatcher illusion and facial features

Benjamin de Haas published a study in the Journal of Vision in which he followed up his previous work on retinotopic priors in face perception. We are used to seeing eyes in the upper visual field and mouths in the lower visual field. His experiments suggest that this could explain at least some of the Thatcher illusion. This argues against a strict role of holistic processing in that illusion.

Thatcher Illusion
The Thatcherized face (top right) appears grotesque but when inverted (bottom left) it is far less so

 

de Haas, B, & Schwarzkopf, DS (2018) Feature-location effects in the Thatcher illusion. Journal of Vision 18(4): 16.

Escher Chairs illusion

Nick Scott-Samuel, George Lovell, Hiroshi Ashida, and Sam published a (very) little article on the Stacking Chairs illusion in iPerception. This was all mainly Nick’s work who discovered that stacking those kinds of chairs produces a very confusing and seemingly geometrically impossible percept:

EscherChairs

Note, a reviewer didn’t like that we called this stimulus Escher Chairs but I will stubbornly continue calling them that. They are very Escherial. Or perhaps Penrosian would be more appropriate?

Scott-Samuel, NE, Ashida, H, Lovell, PG, Meese, TS, & Schwarzkopf, DS (2018). Stacking Chairs: Local Sense and Global Nonsense. i-Perception 9(1).

pRF study on illusory contours

We recently published a study in Scientific Reports using illusory contour and amodal completion (occlusion) stimuli to map population receptive fields in early visual cortex. The signals are very weak but they correspond spatially very well to normal retinotopic maps. We suspect that what these experiments were really mapping is spatially selective attention cued to the position of the mapping stimuli. We thank Rebecca Tyrwhitt-Drake who did the original experiments for her student research project.

Kanizsa

de Haas B, & Schwarzkopf DS (2018). Spatially selective responses to Kanizsa and occlusion stimuli in human visual cortex. Scientific Reports 8: 611.

End of an era

Last photo of the lab before Sam’s move to New Zealand. I hope we can all meet again soon on the same spot of earth wherever it may be!

 

LabBeforeNZ

MAPS method for measuring perceptual biases

Nonie Finlayson published this article in the Journal of Vision in which we investigate the estimates of perceptual biases produced by our Multiple Alternatives Perceptual Search (MAPS) method. Here we compare these biases to those estimated by the traditional method of constant stimuli and also conducted an attentional cuing experiment (done by Andria Papageorgiou for her MSc research project) to test whether biases are influenced by spatially selective attention.

Boxes

Finlayson, NJ, Papageorgiou A, & Schwarzkopf, DS (2017). A new method for mapping perceptual biases across visual space. Journal of Vision 17(9): 5.

 

Reliability of pRF measurements

Former MSc student Jelle van Dijk published a study in NeuroImage in which we quantify the test-retest reliability of population receptive field measurements by comparing mapping experiments separated by several weeks. We found that visual field positions are extremely reliable but second-order parameters, such as pRF size and cortical magnification factor, is far less reliable (although still well correlated across sessions). Control experiments further suggested that these findings do not critically depend on the carrier stimuli used for mapping – but that reliability is a lot better if comparing mapping experiments conducted within the same scanning session. This suggests that changes of the scanning environment over time (both in terms of the setup or the scanner itself) are the greatest source of noise limiting reliability.

Reliability.jpg

van Dijk, JA, de Haas, B, Moutsiana, C, & Schwarzkopf, DS (2016). Intersession reliability of population receptive field estimates. NeuroImage 143: 293–303.

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